Glifozins: what can be the complications?


These oral antidiabetics are generally well tolerated. The risk of complications, rare but severe, requires vigilance.

ketoacidosis

The signs

Nausea, vomiting, severe abdominal pain, intense thirst, difficulty breathing, severe fatigue: each of these symptoms should be considered as a warning signal, regardless of glucose levels.

What has to be done

Stop treatment and contact your doctor or emergency services immediately if these symptoms occur.

Treatment should be discontinued before surgery.

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Urinary and genital infections

The signs

Burning while urinating, frequent urges to urinate, inflammation of the vulva (vulvovaginitis) or glans (balanitis), genital pruritus…

What has to be done

Consult at the slightest urinary or genital symptom to benefit from appropriate treatment and prevent complications.

Urgent medical advice is required in the event of pain, redness and/or swelling in the genital area, especially if these signs are followed by fever.

Foot infections

The signs

Redness, warmth or swelling in the feet or toes.

The wounds are often mild or even painless, but do not heal.

What has to be done

Ensure rigorous hygiene of the feet and regularly monitor their skin condition.

Consult in case of wound, even superficial, or skin lesion.

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Dehydration and hypotension

The signs

Feeling weak, dizzy or lightheaded, mild malaise, fatigue and weight loss.

What has to be done

Drink water, avoid alcohol.

Do not move too quickly from lying down to standing up (orthostatic hypotension).

Consult the doctor in case of frequent or important symptoms.

To know

Glfozins, or SGLT2 inhibitors, are drugs used in the management of type 2 diabetes. This is the newest class of oral antidiabetics. They promote the elimination of glucose by the kidneys.

These drugs have demonstrated their interest in cardiovascular and renal protection in patients at an advanced stage of their diabetes. They are indicated in the management of heart failure and chronic renal failure.

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